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Top 9 Luxury Mekong River Cruises to Vietnam and Cambodia (2025 - 2026)

If you're dreaming of a luxurious and immersive experience in Southeast Asia, a Mekong River cruise between Vietnam and Cambodia is the perfect way to explore the region’s rich culture, history, and landscapes in comfort. The Mekong River, one of the world’s longest and most legendary rivers, winds its way through scenic rural villages, ancient temples, and bustling markets - making it a perfect destination for cultural travelers and cruise lovers alike.

To help you plan your perfect river journey, we’ve curated a list of the top 9 luxury Mekong River cruises offering premium services, elegant ships, and unforgettable itineraries between Ho Chi Minh City (Saigon) and Siem Reap or Phnom Penh.

1. Jahan Cruise - Best for Colonial Luxury & Heritage Travel

Operated by Heritage Line, The Jahan Cruise is widely regarded as one of the most luxurious Mekong River cruises. Inspired by Indian Mughal architecture and colonial charm, this 26-cabin vessel features private balconies, a spa, an outdoor jacuzzi, and a stunning sundeck pool.

🛏️ Highlights: Superior rooms with river views, Indian-themed interiors, top-notch hospitality
🌍 Route: Saigon to Siem Reap or reverse


2. Jayavarman Cruise - A Floating Boutique Art Hotel

Also from Heritage Line, Jayavarman Cruise blends French colonial aesthetics with traditional Khmer décor, creating a luxurious yet artistic ambiance. With 27 spacious cabins, open-air lounges, and immersive local excursions, it's ideal for travelers who value both comfort and culture.

🛏️ Highlights: Private balconies, art-focused design, fine dining

🌍 Route: Vietnam–Cambodia (7 to 8-day cruises)


3. Mekong Princess Cruise – Ultimate Boutique River Experience

With only 12 suites, the Mekong Princess Cruise offers one of the most exclusive experiences on the river. Designed in French colonial style, this elegant vessel includes an on-board spa, observation deck, and unique off-the-beaten-path itineraries.

🛏️ Highlights: Boutique setting, high-end service, personalized excursions

🌍 Route: Phnom Penh to Saigon (4 to 8 days)

Perfect for couples and honeymooners seeking privacy and style.

 

4. Mekong Navigator Cruise - Sophisticated Elegance

Mekong Navigator combines contemporary design with classic colonial charm. Featuring 34 beautifully appointed suites, this 5-star Mekong cruise delivers excellent service, fine dining, and curated excursions to floating villages, local temples, and markets.

🛏️ Highlights: Elegant interiors, French-inspired suites, spa & fitness center

🌍 Route: Saigon to Siem Reap (8 days)

 

5. Mekong Pandaw Cruise - For Traditional River Lovers

Built in the spirit of classic 1920s riverboats, Mekong Pandaw offers a nostalgic and immersive journey. Known for active itineraries including biking and cooking classes, this cruise is perfect for adventurous travelers who want a deeper connection with the Mekong’s culture.

🛏️ Highlights: Traditional design, authentic local activities, small-group tours

🌍 Route: Ho Chi Minh City to Siem Reap

 

6. Aqua Mekong Cruise - Ultra-Luxury with Designer Appeal

Designed by award-winning architect Noor Design, Aqua Mekong is a floating 5-star hotel with 20 suites offering floor-to-ceiling windows and contemporary interiors. With gourmet cuisine, a cinema under the stars, spa, gym, and curated shore excursions, this cruise is ideal for those seeking all-inclusive luxury.

🛏️ Highlights: Designer suites, guided bike tours, eco-friendly practices

🌍 Route: Ho Chi Minh to Phnom Penh or Siem Reap

📈 Best for: High-end travelers and design lovers

 

7. RV Amalotus Cruise – Large Ship with All-Inclusive Perks

As one of the largest vessels on the Mekong, RV Amalotus Cruise offers comfort, space, and a wide range of amenities. With 62 cabins and a large crew, this cruise is ideal for travelers seeking a full-service, social cruise atmosphere.

🛏️ Highlights: Private balconies, inclusive excursions, cultural performances

🌍 Route: Ho Chi Minh City to Phnom Penh/Siem Reap

 

8. RV La Marguerite Cruise – Classic French-Indochina Experience

Combining colonial elegance and authentic charm, La Marguerite offers 46 cabins and refined service along with traditional décor and Vietnamese-Cambodian dining. A Jacuzzi, spa, and stylish lounges complete the experience.

🛏️ Highlights: In-room bathtubs with a view, warm atmosphere, curated tours

🌍 Route: Vietnam to Cambodia (7 to 8 nights)
 

9. Mekong Eyes Explorer - Best Value Luxury

For travelers seeking a balance between affordability and comfort, Mekong Eyes Explorer Cruise is a top pick. Featuring 16 cabins (including panoramic suites), the vessel provides excellent service, exciting daily excursions, and scenic routes through the Mekong Delta and into Cambodia.

🛏️ Highlights: Hand-crafted wood cabins, riverfront balconies, onboard chef

🌍 Route: Southern Vietnam to Phnom Penh

 

✨ How to Choose the Best Mekong Cruise for You?

When picking a Mekong River cruise between Vietnam and Cambodia, consider these key factors:

  • Itinerary length (3 to 10 days)
  • Preferred route: Saigon to Phnom Penh or Siem Reap
  • Cabin style: modern vs. traditional
  • Onboard amenities: spa, gym, jacuzzi, dining
  • Group size: boutique vs. larger cruise ships

Not sure which cruise is for you?

Tell us your travel dates, group size & budget. We’ll match you with your perfect Mekong cruise.

📩 info@vietexquisitetravel.com | 📞 +84 389895768

🌐 https://vietexquisitetravel.com/mekong-cruises

 
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